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Journal of Multidisciplinary Applied Natural Science

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Scopus CiteScore 2024

4.8

Calculated on 05 May, 2025

SJR 2024

0.31

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Journal of Multidisciplinary Applied Natural Science

##plugins.themes.gdThemes.general.eIssn##: 2774-3047


bol: 4 zk: 1 (2024) Articles https://doi.org/10.47352/jmans.2774-3047.204

Green Synthesis of ZnO Nanoparticles using Abelmoschus esculenthus L. Fruit Extract: Antioxidant, Photoprotective, Anti-inflammatory, and Antibacterial Studies

Christina Astutiningsih Tias Eka Rahmawati Nanik Astutik Rahman Meri Meri

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Christina Astutiningsih

https://orcid.org/0000-0001-7264-1905
  • christinaastutiningsih@gmail.com
  • Department of Pharmaceutical and Food Analyst, STIFAR Yayasan Pharmasi, Semarang-50192 (Indonesia)
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Tias Eka Rahmawati

https://orcid.org/0009-0002-5043-6702
  • tiasekarahmawati@gmail.com
  • Department of Pharmaceutical and Food Analyst, STIFAR Yayasan Pharmasi, Semarang-50192 (Indonesia)
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Nanik Astutik Rahman

https://orcid.org/0000-0002-3999-0019
  • nanik.astuti@lecturer.itn.ac.id
  • Department of Chemical Engineering, Institut Teknologi Nasional Malang, Malang-65152 (Indonesia)
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Meri Meri

https://orcid.org/0000-0001-8851-7650
  • meri@universitas-bth.ac.id
  • Department of Medical Laboratory Technology, Universitas Bakti Tunas Husada, Tasikmalaya-46196 (Indonesia)
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##plugins.themes.gdThemes.publishedIn##: urtarrilak 30, 2024

Laburpena

Nanoparticles are extensively studied for their promising biological properties. In this study, the fruit extract of Abelmoschus esculenthus L. was used as a chelating agent for the synthesis of zinc oxide nanoparticles (ZnOPs-AE) using a zinc acetate solution. The prepared ZnOPs-AE were identified and characterized using UV-vis spectroscopy, Fourier-transformed infrared spectroscopy (FTIR), particle size analyzer (PSA), scanning electron microscopy (SEM), and energy dispersive spectrum (EDS). The green synthesized ZnOPs-AE were evaluated for their antioxidant, photoprotective, anti-inflammatory, and antibacterial activities. The synthesized nanoparticles showed an intensity peak at 370 nm in the UV-vis spectrum. The FTIR result shows the presence of O-H, C=O, C-O, C-OH, and C=C chelating functional groups on the surface of nanoparticles. The size of ZnOPs-AE was determined using a PSA with particle size distribution of 102.2 nm. The ZnOPs-AE were shown to be spherical by SEM analysis and composition was 82.11% and 14.79% for Zn and O, respectively. The antioxidant properties of ZnOPs-AE showed significant antioxidant potential in DPPH, ABTS, and FRAP assays compared to the quercetin standard. The photoprotection activity test showed a SPF value of 19.63, the percentage of erythema transmission was 5.98%,  and the percentage of pigmentation transmission was 5.62%. The ZnOPs-AE showed good anti-inflammatory with the synthesized nanoparticle performing activity between positive control and the fruit extract of Abelmoschus esculenthus L. Also, the ZnOPs-AE exhibited good antibacterial activity against Staphylococcus aureus (20.78 mm) and Pseudomonas aeruginosae (11.13 mm). Overall, the results highlight the effectiveness and potential of ZnOPs-AE for biological application.

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